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1

The Importance of Preclinical Trial Timing – a Potential Reason for the Disconnect between mouse Studies and Human Clinical Trials in ALS

Qiongman Kong, Sarah Carothers, Yueming Chang, Chien-Liang Glenn Lin

Journal:

CNS Neuroscience & Therapeutics

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

2

Pyridazine-derivatives enhance structural and functional plasticity of tripartite synapse via activation of local translation in astrocytic processes

Foster, Joshua B., Zhao, Fangli, Wang, Xueqin, Xu, Zan, Lin, Kuanhung, Askwith, Candice C., Hodgetts, Kevin J., Glenn Lin, Chien-liang

Journal:

Year:

2018

Language:

english

File:

PDF, 7.77 MB

english, 2018

3

The presence of rRNA sequences in polyadenylated RNA and its potential functions

Qiongman Kong, Michael P. Stockinger, Yueming Chang, Hirofumi Tashiro, Chien-liang Glenn Lin

Journal:

Biotechnology Journal

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

4

10.1038/35065084

Lin, Chien-liang Glenn, Orlov, Irina, Ruggiero, Alicia M., Dykes-Hoberg, Margaret, Lee, Andy, Jackson, Mandy, Rothstein, Jeffrey D.

Journal:

Year:

2001

Language:

english

File:

PDF, 309 KB

english, 2001

5

Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus

Qiongman Kong, Kou Takahashi, Delanie Schulte, Nathan Stouffer, Yuchen Lin, Chien-Liang Glenn Lin

Journal:

Neurobiology of Disease

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

6

Selection of monoclonal antibodies for probing of functional intermediates in incision of UV-irradiated DNA by Uvr(A)BC endonuclease from Escherichia coli

Oleg I Kovalsky, Chien-liang Glenn Lin, Lawrence Grossman

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 321 KB

english, 1998

7

Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases

Lin, Chien-Liang Glenn, Kong, Qiongman, Cuny, Gregory D, Glicksman, Marcie A

Journal:

Future Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.30 MB

english, 2012

8

Human Glioma Cells and Undifferentiated Primary Astrocytes That Express Aberrant EAAT2 mRNA Inhibit Normal EAAT2 Protein Expression and Prevent Cell Death

Hong Guo, Liching Lai, Matthew E.R. Butchbach, Chien-liang Glenn Lin

Journal:

Molecular and Cellular Neuroscience

Year:

2002

Language:

english

File:

PDF, 448 KB

english, 2002

9

Quantification of oxidized RNAs in Alzheimer's disease

Xiu Shan, Chien-liang Glenn Lin

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

10

Aberrant RNA Processing in a Neurodegenerative Disease: the Cause for Absent EAAT2, a Glutamate Transporter, in Amyotrophic Lateral Sclerosis

Chien-Liang Glenn Lin, Lynn A. Bristol, Lin Jin, Margaret Dykes-Hoberg, Thomas Crawford, Lora Clawson, Jeffrey D. Rothstein

Journal:

Year:

1998

Language:

english

File:

PDF, 608 KB

english, 1998

11

Molecular cloning and expression of the rat EAAT4 glutamate transporter subtype

Chien-Liang Glenn Lin, Anastassios V Tzingounis, Lin Jin, Akiko Furuta, Michael P Kavanaugh, Jeffrey D Rothstein

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 1.16 MB

english, 1998

12

RNA oxidation: A contributing factor or an epiphenomenon in the process of neurodegeneration

Kong, Qiongman, Shan, Xiu, Chang, Yueming, Tashiro, Hirofumi, Lin, Chien-Liang Glenn

Journal:

Free Radical Research

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

13

Methyl-β-cyclodextrin but not retinoic acid reduces EAAT3-mediated glutamate uptake and increases GTRAP3-18 expression

Matthew E. R. Butchbach, Hong Guo, Chien-liang Glenn Lin

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 151 KB

english, 2003

14

Effects of axon degeneration on oligodendrocyte lineage cells: Dorsal rhizotomy evokes a repair response while axon degeneration rostral to spinal contusion induces both repair and apoptosis

Fang Sun, Chien-Liang Glenn Lin, Dana Mctigue, Xiu Shan, C. Amy Tovar, Jacqueline C. Bresnahan, Michael S. Beattie

Journal:

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

15

The Identification and Characterization of Oxidized RNAs in Alzheimer's Disease

Shan, Xiu, Tashiro, Hirofumi, Lin, Chien-liang Glenn

Journal:

Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 250 KB

english, 2003

16

Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease

Takahashi, Kou, Foster, Joshua B., Lin, Chien-Liang Glenn

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

17

Oxidative damage to RNA: mechanisms, consequences, and diseases

Qiongman Kong, Chien-liang Glenn Lin

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 739 KB

english, 2010

18

Structure–activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators

Xuechao Xing, Ling-Chu Chang, Qiongman Kong, Craig K. Colton, Liching Lai, Marcie A. Glicksman, Chien-Liang Glenn Lin, Gregory D. Cuny

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

19

Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3–18

Matthew E.R Butchbach, Liching Lai, Chien-liang Glenn Lin

Journal:

Year:

2002

Language:

english

File:

PDF, 714 KB

english, 2002

20

Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer’s disease: a preclinical study in rTg4510 mice

Foster, Joshua B., Lashley, Rashelle, Zhao, Fangli, Wang, Xueqin, Kung, Nydia, Askwith, Candice C., Lin, Lin, Shultis, Michael W., Hodgetts, Kevin J., Lin, Chien-Liang Glenn

Journal:

Alzheimer's Research & Therapy

Year:

2019

Language:

english

File:

PDF, 6.39 MB

english, 2019

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